Scarlata, Richard M. (MC1964)
The following article is about Jim Quigley, former denizen of Marble Hill, Prepster 1960, Manhattan College 1965. Metastasis mechanism uncovered by Scripps scientists
Metastasis mechanism uncovered by Scripps scientists
By BRADLEY J. FIKES
Posted: Thursday, January 26, 2012 2:30 pm
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Metastasis is one of the most frightening words a person with cancer can hear. A team led by scientists at The Scripps Research Institute says it has figured out an important part of how metastasis takes place.
A protein linked to metastasis called CDCP1 helps cancers spread only after it is broken up by enzymes called serine proteases, according to James P. Quigley, a Scripps research professor who led the study.
“This cleavage triggers a signaling cascade in the tumor cell that blocks apoptosis,” Quigley said in a Scripps press release about the study. A paper on the research was published last month in the journal Oncogene.
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[JR: A great find of a great discovery. That's why for this effort of Jasper Jottings to work, readers have to "rat out" their fellow alumni. Wow. What an accomplishment. My maternal Grandmother died of colon cancer and my Mom had a near miss. Maybe this will prevent it happing to someone else. A truly great story and the automagic filters would have missed it completely. Google has a a lot of work to do in search.]
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